Encourages students to think independently.
Wim Van den Ende is a Professor in the Department of Biology, Faculty of Science at KU Leuven, serving as Principal Investigator and Head of the Sugar Metabolism group within the Laboratory of Molecular Plant Biology. He obtained his degree as an Agronomical Engineer in 1991 from KU Leuven with great distinction and his PhD in Bio-Science Engineering in 1996 from the same university. His research specializes in sugar and carbohydrate metabolism across plants and microorganisms, with a primary focus on fructans, including inulin and levan. Van den Ende examines fructan biosynthesis, degradation enzymes such as fructan exohydrolases and inulosucrases, and their functions in plant abiotic and biotic stress responses, including drought tolerance, cold acclimation, and defense against pathogens like Botrytis cinerea and Phytophthora capsici.
Through his studies on 'sweet immunity,' Van den Ende has demonstrated how fructan oligosaccharides prime crops such as chicory, lettuce, tomato, rocket, and wheat for enhanced resistance to fungal infections via apoplastic sugar dynamics and ethylene-dependent mechanisms. His investigations also cover sugar signaling, reactive oxygen species modulation, autophagy, and environmental influences like light and CO2 on stomatal function and metabolism. With over 200 publications and more than 14,500 citations, key works include the book The Book of Fructans (2023), 'Fructan oligosaccharide priming associates with apoplastic sugar dynamics and improved resistance against Botrytis cinerea in chicory' (2022), 'Sweet Immunity Aspects during Levan Oligosaccharide-Mediated Priming in Rocket against Botrytis cinerea' (2022), and 'Fructans of the Salty World' (2018). He teaches courses on plant development, metabolic regulation, functional plant biology, and biomolecular interactions, and is a member of the KU Leuven Plant Institute, contributing to projects on crop protection and sustainable agriculture.