"Bioinformatician"

Job Details

Bioinformatician

University Overview

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn's distinctive interdisciplinary approach to scholarship and learning. As an employer Penn has been ranked nationally on many occasions with the most recent award from Forbes who named Penn one of America's Best Large Employers in 2023.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

Posted Job Title Bioinformatician Job Profile Title Bioinformatician A Job Description Summary Applies principles and methods of bioinformatics to assist scientists, principal investigators and other laboratory team members. Discusses study design with research teams and applies bioinformatics tools to visualize, analyze, manipulate or interpret molecular data. May build and maintain databases for processing and analyzing genomic or other biological information. Job Description Job Responsibilities

• Genomics and data science expertise in Next‑Generation Sequencing analysis, from QC to modeling and interpretation
• Advanced R workflows (tidyverse, stats, visualization) and scalable scripting in Python for reproducible analysis
• Robust differential gene expression and pathway/functional enrichment (pseudobulk + single-cell designs)
• Single-cell and spatial omics integration and latent modeling with scVI for batch correction and label transfer
• Regulatory genomics and motif analysis using tools from MEME Suite or HOMER.
• Cloud-native NGS workflow execution using AWS Batch and object-storage patterns with Amazon S3
• Handling of large genomics and multi-omics matrices (HDF5, loom, h5ad)
• Containerized pipeline and environment development (Docker, Apptainer/Singularity) for HPC and cloud portability
• Querying, transforming, and summarizing major genomics resources (GTEx, GEO)
• Version-controlled project delivery in Git-based repositories for transparent, documented collaboration
• Multi-species ortholog mapping and annotation harmonization for integrative genomics analysis
• Publication-grade visualization using ggplot2 and ComplexHeatmap
• Emerging leadership, mentorship, and multidisciplinary collaboration in international genomics research teams
• Strong verbal and written communication skills and developing leadership skills for working with multidisciplinary teams and with international colleagues.
• Other duties and responsibilities as assigned

Qualifications

• Bachelor of Science and 3 to 5 years of experience or equivalent combination of education and experience is required.

This position is contingent upon grant funding.

Job Location - City, State Philadelphia, Pennsylvania Department / School Perelman School of Medicine Pay Range $57,500.00 - $77,716.00 Annual Rate Salary offers are made based on the candidate's qualifications, experience, skills, and education as they directly relate to the requirements of the position, and in alignment with salary ranges based on external market data for the job's level. Internal organization and peer data at Penn are also considered. Equal Opportunity Statement

The University of Pennsylvania is an equal opportunity employer. Candidates are considered for employment without regard to race, color, sex, sexual orientation, religion, creed, national origin (including shared ancestry or ethnic characteristics), citizenship status, age, disability, veteran status or any class protected under applicable federal, state or local law.

Special Requirements Background checks may be required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job. University Benefits

• Health, Life, and Flexible Spending Accounts: ...
• Tuition: ...
• Retirement: ...

To learn more, please visit: https://www.hr.upenn.edu/PennHR/benefits-pay