MRC Postdoctoral Research Scientist

MRC Laboratory of Medical Sciences – Development and Transcriptional Control

Fixed term (2 years) with potential for extension

About us

The MRC Laboratory of Medical Sciences (https://lms.mrc.ac.uk/) is a leading institute for discovery science, focused on the fundamental biology that drives health and disease. Based in London and closely linked to Imperial College London, LMS offers a collaborative, interdisciplinary environment with strengths in epigenetics, developmental biology, and quantitative approaches. Our researchers are supported by cutting-edge facilities (https://lms.mrc.ac.uk/facilities/) and a strong commitment to scientific training and career development.

About the role

Understanding how the right cell types form in the right position and proportion during embryonic development represents one of the most important open questions in developmental biology. The Development and Transcriptional Control group (https://lms.mrc.ac.uk/research/development-and-transcriptional-control/) is tackling this challenge by investigating how cell identity is established and how it shapes the mammalian body. Our multidisciplinary approach integrates mouse developmental genetics, stem cell-based models of development, and genome engineering. These systems support quantitative and mechanistic studies, allowing us to address questions across scales: from the function of cis-regulatory elements, to the morphogenesis of the body plan (Amblard et al., Dev Cell, 2025). The ideal candidate will be highly motivated to develop new tools and methodologies to uncover the gene regulatory principles of mammalian development. The role offers opportunities to pursue independent research ideas within the lab’s core focus, with strong support for career development and scientific training.

About you

We’re seeking a highly motivated postdoctoral scientist to develop new tools and methodologies to dissect the function of cis-regulatory elements and how they impact mammalian development. The role offers opportunities to pursue independent research ideas within the lab’s core focus, with strong support for career development and scientific training. We welcome applicants eager to join and contribute to a collaborative and multidisciplinary team environment.

What we offer

As well as the exciting opportunities this role presents, we also offer defined benefit pension scheme and excellent holiday entitlement (30 days plus 2.5 privilege days & 8 bank holidays), family friendly policies (6 months full pay maternity & adoption leave), a range of shopping/travel discounts, access to our Employee Assistant Programme Scheme, Health and Wellbeing Support and a salary sacrifice cycle to work scheme. Please follow this link to find out more - Benefits

How to apply

For full details of the post and to complete an online application, please click the ‘Apply’ button above and upload your CV, names and contacts of two scientific references along with a cover letter stating why you are applying for this role (providing evidence against the requirements of the job as per the job description and person specification). Applications without a cover letter will not be accepted. Please quote reference number LMS 2663. The final appointment will be subject to pre-employment screening. Please note that applications may be reviewed by both LMS and Imperial staff. Additional allowances comprise a £1,000 lump sum Settlement Allowance plus a yearly Training Allowance of £850 in the first year, paid in monthly instalments. The Training Allowance increases to £1,300 in year two.

Location:LondonSalary:£41,344 plus London allowances £5,385 per annum*Hours:Full TimeContract Type:Fixed-Term/ContractPlaced On:15th July 2025Closes:13th September 2025Job Ref:LMS 2663