Post-Doctoral Research Fellow

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world's leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world's deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

A new Post-Doctoral Research Fellow position is available in Andrew Fiore-Gartland's group in Biostatistics, Bioinformatics and Epidemiology (BBE) within VIDD at Fred Hutch in Seattle, WA. The group works on multiple projects investigating the immunological correlates of protection for novel tuberculosis vaccine candidates. Understanding the factors that impact vaccine response and identifying the features of the immune response that confer protection can provide critical feedback for vaccine development. As part of the HIV Vaccine Trials Network supported by the NIH Division of AIDS and the Vaccine & Immunology Statistical Center (VISC), supported by the Gates Foundation we are leading major computational efforts to integrate immunological datasets generated from human clinical trials.

Cover letters are highly desired from applicants. Please address to Dr. Andrew Fiore-Gartland and include a short statement of research interests.

Responsibilities

Research will focus on development and application of methods, algorithms and tools for biostatistics and computational biology. A primary goal will be integration of single-cell and/or high-dimensional datasets measured from the same individuals, to address the dual goal of generating biological insights and developing novel biomarkers from human clinical trials. Analysis datasets include those generated by multicolor flow cytometry, transcriptomics/RNAseq, T cell receptor repertoire sequencing, single-cell/CITE-seq/ATAC-seq, and multiplexed systems serology, among others. With this data we have the potential to understand the immunological mechanisms of vaccines and to accelerate efforts to improve their efficacy and get them to the clinic.

Qualifications

MINIMUM QUALIFICATIONS:

• PhD (or equivalent) in biology, applied mathematics, statistics, computer science or related field.
• A proven track-record of peer reviewed publications, and programming experience in Python or R.
• An appetite to understand and analyze new types of data, and a commitment to scientific rigor.

PREFERRED QUALIFICATIONS:

• Publication demonstrating development or enhancement of statistical or bioinformatic tool or software (provide publication and github links).

Cover letters are highly desired from applicants. Please address to Dr. Andrew Fiore-Gartland and include a short statement of research interests.