"Postdoctoral Fellow, Medicinal Chemistry, School of Pharmacy"

Job Details

The School of Pharmacy has a 125-year tradition beginning with the Medical College of Virginia and continuing to the present. Ranked in the top 20 Schools of Pharmacy nationwide, the school is dedicated to graduating outstanding future pharmacists and scientists who will improve human health, foster exemplary research, and provide sustaining contributions to inter-professional patient care. The School of Pharmacy is committed to fostering a climate where the success of all people is supported and celebrated.

Benefits: All VCU employee types are eligible for a wide array of benefits to support you during your employment at VCU. Consult the benefits website for information on benefits eligibility according to employee type.

Unit: School Of Pharmacy MBU

Department: Medicinal Chemistry (Pharmacy)

Duties & Responsibilities:

• Design novel scaffolds and plan efficient, scalable synthetic routes.
• Synthesize and purify target compounds; troubleshoot challenging synthetic steps.
• Characterize compounds by NMR, LC/HRMS, HPLC, IR and related methods.
• Analyze Structure-activity-relationships and collaborate with biology/computation to prioritize next cycles.
• Contribute to biochemical/biophysical assay planning and data interpretation.
• Maintain rigorous notebooks; present results; assist with manuscripts and proposals.

Qualifications:

Minimum Qualifications

• Ph.D. in Synthetic Organic Chemistry or Medicinal Chemistry (by start date)
• Demonstrated expertise in synthetic route design and complex molecule synthesis
• Proficiency with NMR, LC/HPLC, MS, IR and data analysis for structural elucidation
• Design, synthesis, and biological characterization of novel lead compounds to develop drug candidates in treating various types of diseases
• Familiarity with computational chemistry and structure-based molecular design
• Excellent written and oral communication skills.
• Demonstrated ability to work in and foster an environment of respect, professionalism and civility with a population of faculty, staff, and students from all backgrounds and experiences, or a commitment to do so as a postdoctoral fellow at VCU.

Preferred Qualifications

• Experience with GPCR-focused programs and small-molecule hit-to-lead workflows.
• Exposure to biochemical/biophysical assays (binding/functional) and ADME-relevant considerations.
• Exposure to basic animal handling.
• Track record of publications and effective cross-disciplinary collaboration.

Salary Range: $50,000

FLSA Exemption Status: Exempt

Hours per Week: 40

ORP Eligible: Yes

Flexible Work Arrangement: Fully Onsite

Rank: Non Faculty

Contact Information: Contact Name: Piyusha Pagare Contact Email: pagarepp@vcu.edu