"Postdoctoral Fellow"

About us

The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions.

To learn more about the Crick, click here.

About the role

The Haematopoietic Stem Cell Lab works on the regulation of human normal haematopoietic stem cell biology and leukemia and the role of the extracellular factors providing by the niche.

We are looking for a productive and motivated Postdoctoral Fellow with a desire to work in a congenial, dynamic and collaborative research team. You will be part of the team of researchers working in the Haematopoietic Stem Cell laboratory under the direction of Prof Dominique Bonnet.

The group is interested in studying normal human Haematopoietic Stem Cells (HSCs) and Leukaemic Stem Cells (LSCs). At present we are investigating the relationship between normal HSCs, LSCs and their microenvironment. We are also interested in understanding how pre-leukaemic mutations provide a clonal advantage overtime, what are the external factors involved in this selection and how to potential revert it.

As a Postdoctoral fellow in the HSC team, you will be responsible for leading an independent research project within the lab, playing a key role in driving the overall direction of the project under the supervision of Prof D Bonnet.

See here for more details of research projects currently being undertaken in HSCL lab.

Please see the full job description here.

What you will be doing

As a Postdoctoral Fellow at the Crick, you will:

• Design and perform experiments, and analysis data, with the strongest possible research integrity.
• Keep up with relevant scientific literature to identify key challenges in the field.
• Reporting, presenting and discussing results with people in the group during lab meeting
• Presenting and reporting results with D Bonnet in a regular basis.
• Collaborate with others in the lab and/or institute and with the scientific facilities
• Collaborate with external researchers if /when the project requires it.

About you

You will bring

• PhD on stem cell and/or cancer biology,
• Experience FACS analysis/sorting
• Experience in molecular biology
• Experience in modulating gene expression via lentivirus and/or Crisp-Cas9 editing,
• Experience on haematopoietic field

About Working at the Crick

Our values

• We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We’re not afraid to do things differently.
• We are open. We’re highly collaborative and interactive, and make sure our activities are visible to the outside world.
• We are collegial. We show respect for one another, work cooperatively and support the wider community.

At the Crick, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. If you need assistance with your application, please contact people@crick.ac.uk

To read more about our EDI approach, click here.

What will you receive?

We value our team members and are proud to offer an extensive range of benefits to support their well-being and development. You can find out more about what we offer here.