"Postdoctoral Research Assistant - UOD2014"

The Miller lab seeks a post-doctoral fellow to study the conserved cellular machinery that mediates the first step of protein secretion, export from the endoplasmic reticulum. We aim to understand how cells maintain selectivity when handling a vast diversity of protein sequence and structure. Specifically, we use genetic and biochemical approaches to dissect the molecular mechanisms by which cargo proteins are selectively captured into nascent vesicles. The project uses a blend of mechanistic approaches that dissect protein-protein interactions for export receptors using yeast as a model system, complemented by cell-based approaches to reveal the spectrum of proteins that engage these machineries and the phenotypic consequences of perturbed interactions.

The School of Life Sciences at the University of Dundee is a world-class academic institution with a reputation for the excellence of its research, its high quality teaching and student experience, and the strong impact of its activities outside academia. With 900 staff from over 60 countries worldwide the School provides a dynamic, multi-national, collegiate and diverse environment with state-of-the-art laboratory, technology and teaching facilities.

Your priorities will include:

• Play a lead role in establishing the research project
• Undertake a broad range of biochemical and genetic approaches
• Undertake supervision of Honours and M.Sc. students within the group

Who we're looking for:

• Ph.D. in a yeast genetics and/or cell biology
• Major contributions to at least one research paper in a peer-reviewed journal
• Excellent written and oral communication skills, including excellent interpersonal skills
• Independent, creative and ambitious thinkers
• Experience with fungal genetics and biochemistry

For further information about this position please contact Prof. Liz Miller at emiller003@dundee.ac.uk. To find out more about Unit please visit: www.dundee.ac.uk/mcdb.