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University of Oxford

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Centre for Human Genetics, Building for Genomic Medicine, Old Road Campus, Roosevelt Drive, Headington, Oxford, OX3 7BN

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"Postdoctoral Research Scientist"

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Postdoctoral Research Scientist

Research Grade 7

09-Mar-2026 12:00

Location

Oxford, OX3 7BN, UK

University of Oxford

Type

Full-time Fixed-term (28 months)

Salary

£39,424 - £47,779 p.a. (pro rata + £1,730 Oxford weighting)

Required Qualifications

PhD/DPhil in immunology or related
T/B cell immunology expertise
Mucosal/barrier tissues experience
Single-cell transcriptomics analysis
Human samples & translational research
Publications & organizational skills

Research Areas

Inflammatory Bowel Disease
Immune cell regulation
Genomics & immunology
Single-cell technologies
T/B cell responses
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Postdoctoral Research Scientist

We are seeking to appoint two Postdoctoral Research Scientists to join the Nuffield Department of Medicine and work on cutting-edge research into inflammatory bowel disease. You will explore how immune cells behave within the intestinal environment and how genetic variation disrupts immune regulation, leading to chronic inflammation. By combining genomics, immunology and advanced single-cell technologies, the project aims to uncover the cellular networks that drive disease and translate these discoveries into more personalised and effective treatments.

You will be responsible for leading experimental and analytical work to dissect T and B cell responses within human intestinal tissue, using approaches such as advanced flow cytometry, immunohistochemistry, and antibody profiling. You will develop complex in vitro disease models, analyse multi-omic datasets, and communicate findings through publications, presentations and collaborative projects. Alongside your own research, you will contribute to project coordination, help develop new research ideas and funding proposals, and maintain high standards of data management and reproducibility.

It is essential that you hold a PhD/DPhil (or are close to completion) in immunology or a closely related discipline and have strong expertise in T and/or B cell immunology, ideally within mucosal or barrier tissues. You will be experienced in analysing complex computational datasets such as single cell transcriptomics, and be able to work both independently and collaboratively in a multidisciplinary environment. A clear track record of scientific productivity, excellent organisational skills, and the ability to communicate research effectively in writing and in person are essential, as is experience working with human samples in translational research.

Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date.

This position is offered full time on a fixed term contract for 28 months and is funded by The Leona M. and Harry B. Helmsley Charitable Trust.

Only applications received before 12 midday on 9 March 2026 will be considered. Please quote 184623 on all correspondence.

Contact Person: Phoebe Astbury | Vacancy ID: 184623 | Closing Date & Time: 09-Mar-2026 12:00 | Pay Scale: RESEARCH GRADE 7 | Contact Email: recruitment@ndm.ox.ac.uk | Salary (£): Research Grade 7: Salary in range £39,424 - £47,779 per annum (pro rata). This is inclusive of a pensionable Oxford University Weighting of £1,730 per year (pro rata)

Location: Centre for Human Genetics, Building for Genomic Medicine, Old Road Campus, Roosevelt Drive, Headington, Oxford, OX3 7BN

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Frequently Asked Questions

🎓What qualifications are essential for this Postdoctoral Research Scientist role?

You must hold a PhD/DPhil (or be close to completion) in immunology or a related field, with strong expertise in T and/or B cell immunology, ideally in mucosal or barrier tissues. Experience analyzing single-cell transcriptomics and working with human samples in translational research is required. A proven track record of publications is essential. See postdoc success tips and academic CV guide.

🔬What are the main responsibilities in this immunology postdoc position?

Lead experimental work on T and B cell responses in human intestinal tissue using flow cytometry, immunohistochemistry, and antibody profiling. Develop in vitro disease models, analyze multi-omic datasets, publish findings, coordinate projects, and contribute to funding proposals. Maintain data reproducibility. Explore postdoc research strategies.

📝How do I apply for this Oxford University Postdoctoral Research Scientist job?

Apply online via the University of Oxford portal, uploading a CV and supporting statement addressing each selection criterion with examples. Quote Vacancy ID: 184623. Only CV and statement accepted initially. Deadline: 09-Mar-2026 12:00. Contact: recruitment@ndm.ox.ac.uk. Review CV tips.

💰What is the salary, contract, and location for this IBD research postdoc?

Salary: Research Grade 7 £39,424 - £47,779 p.a. (pro rata, incl. £1,730 Oxford weighting). Contract: Full-time, fixed-term 28 months, funded by Leona M. and Harry B. Helmsley Charitable Trust. Location: Centre for Human Genetics, Oxford, OX3 7BN. No visa sponsorship mentioned.

🧬What research focus and skills are needed for this single-cell immunology role?

Focus on inflammatory bowel disease: immune cells in intestinal environment, genetic variation in immune regulation, using genomics, immunology, and single-cell technologies. Skills: flow cytometry, multi-omics analysis, independent/collaborative work. Ideal for mucosal immunology experts. Check research jobs and postdoc thriving guide.

🩺Is experience with human samples required for this Oxford postdoc?

Yes, experience working with human samples in translational research is essential, alongside T/B cell responses in intestinal tissue and computational datasets like single-cell transcriptomics. Multidisciplinary collaboration expected.
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