Research Associate in Cardio-Immunology
About The Role
This is an exciting opportunity to work on cardio-immunology within King’s BHF Centre of Excellence. Myocardial infarction is the commonest cause of heart failure and there is compelling evidence implicating excessive inflammation as a key contributor. Cardiac-resident leucocyte subsets are important mediators of the inflammatory response to cardiac injury, but it is not clear how signalling in these cells is regulated.
The project aims to delineate signalling in leucocytes after myocardial infarction using in vivo models, in vitro experiments, and multi-platform ‘omics’ approaches. These studies will provide invaluable knowledge on the regulation of inflammation after MI. We aim to identify and target novel signalling pathways and genomic and transcriptional regulators of inflammation that we can translate to the bedside to alleviate progression to heart failure.
We are seeking a motivated and enthusiastic candidate to join our pre-clinical and translational research. The successful applicant will be expected to develop and undertake research of high quality consistent with the aims of the project. They will contribute to all facets of the lab, including managing specific work packages and working as part of a multi-disciplinary team.
This is a full-time post (35 hours per week), and you will be offered a fixed term contract until 31st March 2028.
Research staff at King’s are entitled to at least 10 days per year (pro-rata) for professional development. This entitlement, from the Concordat to Support the Career Development of Researchers, applies to Postdocs, Research Assistants, Research and Teaching Technicians, Teaching Fellows and AEP equivalent up to and including grade 7. Visit the Centre for Research Staff Development for more information.
About You
To be successful in this role, we are looking for candidates to have the following skills and experience:
Essential criteria
- Have proven expertise in working with primary cells; be able to perform routine molecular biology protocols, such as DNA isolation, PCR, RT-PCR, cell culture and treatment, cell fractionation, flow cytometry, ELISA, and functional assays.
- Possess scientific integrity and understanding of the importance of study design, power calculations, and statistical analysis.
- Commitment to continuing personal and professional development.
- Good written presentation skills, communication skills (written & verbal), and IT skills.
- Ability to work independently and integrate with colleagues, work as part of a team, and undertake a share of group tasks.
- Proven ability to manage own research and administrative activities efficiently, prioritise, meet targets and deadlines, and keep clear and well-organised laboratory notes and records.
Desirable criteria
- Experience of wet lab workflows for bulk and single cell RNA sequencing.
- Hold a Home Office personal licence.
- Experience of genomics and bioinformatic workflows.
Downloading a copy of our Job Description
Full details of the role and the skills, knowledge and experience required can be found in the Job Description document, provided at the bottom of the page. This document will provide information of what criteria will be assessed at each stage of the recruitment process.
Further Information
We pride ourselves on being inclusive and welcoming. We embrace diversity and want everyone to feel that they belong and are connected to others in our community.
We are committed to working with our staff and unions on these and other issues, to continue to support our people and to develop a diverse and inclusive culture at King's.
As part of this commitment to equality, diversity and inclusion and through this appointment process, it is our aim to develop candidate pools that include applicants from all backgrounds and communities.
We ask all candidates to submit a copy of their CV, and a supporting statement, detailing how they meet the essential criteria listed in the advert. If we receive a strong field of candidates, we may use the desirable criteria to choose our final shortlist, so please include your evidence against these where possible.
To find out how our managers will review your application, please take a look at our ‘How we Recruit’ pages.
Grade and Salary: £39,076 - £40,733 per annum inclusive of London Weighting Allowance
Job ID: 130065
Close Date: 17-Dec-2025
Contact Person:Daniel Bromage
Contact Details:daniel.bromage@kcl.ac.uk
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