Rate My Professor Anthony Isles

As a molecular and behavioural neuroscientist, Anthony Isles investigates the contribution of epigenetic mechanisms, particularly imprinted genes, to brain development, function, and behaviour, with emphasis on their roles in neurodevelopmental and neuropsychiatric disorders. His research employs multi-disciplinary approaches including behavioural analysis, neurobiology, and molecular genetics in rodent models, exploring links from placental imprinted genes to maternal behaviour and offspring outcomes. Key publications include 'Imprinted genes and the manipulation of parenting in mammals' (Nature Reviews Genetics, 2023, with R. John and M.J. Higgs), 'The parenting hub of the hypothalamus is a focus of imprinted gene action' (PLoS Genetics, 2023), 'Genomic imprinting effects on brain development and function' (Nature Reviews Neuroscience, 2007, with L.S. Wilkinson and W. Davies), and 'Distinct physiological and behavioural functions for parental alleles of imprinted Grb10' (Nature, 2011). Isles has secured major funding such as the Wellcome Mental Health Award (2025-2030) for cognitive health in psychotic disorders and MRC grants. He serves on editorial boards for Philosophical Transactions of the Royal Society B, Genes Brain and Behavior, and others, and holds roles including member of the Wellcome Brain and Behavioural Sciences Discovery Advisory Group and former trustee of the British Association of Neuroscience. Isles has delivered public lectures at Pint of Science, Cardiff Philosophy Cafe, and MRC Centenary events, and engaged with communities via IPWSO Leadership ECHO on Prader-Willi syndrome.