Rate My Professor Guri Tzivion

Guri Tzivion, Ph.D., serves as Associate Dean for Research and Research Education and Professor of Molecular Biology, Genetics and Immunology in the Department of Molecular Sciences at Windsor University School of Medicine. He is also Course Director for programs in these areas and facilitates hands-on learning in basic sciences through innovative teaching techniques. Tzivion earned his Ph.D. in Immunology and M.Sc. in Immunology and Microbiology from The Hebrew University in Jerusalem, Israel, followed by postdoctoral training in Cancer Biology at Harvard Medical School in Boston, Massachusetts. His career includes prior appointments at the Karmanos Cancer Institute and Department of Pathology, Wayne State University School of Medicine; the Cardiovascular Research Institute, Division of Molecular Cardiology, Texas A&M University System Health Science Center; and the Diabetes Unit, Massachusetts General Hospital. At Windsor, he contributes to the Ph.D. program and delivers lectures on topics such as medical genetics and genomics, medical microbiology and immunology.

Tzivion's research specializations center on molecular signaling pathways critical to cancer biology, including the roles of 14-3-3 proteins in serine/threonine phosphorylation-mediated cellular regulation, Raf kinases in human cancer, and AKT/14-3-3 regulation of FoxO transcription factors and Notch4 nuclear localization. Key publications include "14-3-3 proteins: active cofactors in cellular regulation by serine/threonine phosphorylation" (Journal of Biological Chemistry, 2002), "FoxO transcription factors; Regulation by AKT and 14-3-3 proteins" (Biochimica et Biophysica Acta, 2011), "Raf kinases: function, regulation and role in human cancer" (Biochimica et Biophysica Acta, 2007), "14-3-3 proteins as potential oncogenes" (Seminars in Cancer Biology, 2006), and "PI3K-AKT-FoxO axis in cancer and aging" (Biochimica et Biophysica Acta, 2011). His contributions have advanced understanding of signaling networks regulating cancer pathogenesis, metabolism, and longevity, with work recognized through NIH funding and invitations to speak at conferences such as the Biology of 14-3-3 Proteins Gordon Research Conference.