Rate My Professor Matt Sweet

Professor Sweet's research examines innate immunity, focusing on macrophages and their roles in detecting and responding to infection and inflammation through pathways such as Toll-like receptor signaling, histone deacetylases, immunometabolism, and antimicrobial responses including zinc toxicity against pathogens like Salmonella enterica serovar Typhimurium and uropathogenic Escherichia coli. He has published over 180 journal articles and book chapters, accumulating approximately 22,000 citations, with key works including "Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense" (Science, 2020), "HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages" (PNAS, 2023), and "Inducible antibacterial responses in macrophages" (Nature Reviews Immunology, 2025). His fellowships include an ARC Future Fellowship, two NHMRC Senior Research Fellowships, and the NHMRC Leadership Fellowship, alongside awards such as the Society for Leukocyte Biology prize for mentorship in 2021 and the UQ Award for Excellence in Graduate Research Leadership in 2025. He serves on the editorial boards of the Journal of Leukocyte Biology and Seminars in Cell and Developmental Biology and has contributed to NHMRC grant review panels and numerous conference organizing committees.