"Junior Specialist (Dr. Davide Ruggero and Hao Nguyen Labs)"

Junior Specialist (Dr. Davide Ruggero and Hao Nguyen Labs)

The Ruggero lab (https://ruggerolab.ucsf.edu/) at the Mission Bay campus at UCSF is looking to appoint a Junior Specialist to conduct research related to understanding the molecular mechanisms by which alterations in post-transcriptional regulation and translational control contribute to cancer development. The position will involve a project breeding, genotyping, and analyzing transgenic mouse lines as well as some general laboratory support. The ongoing projects in the lab are focused on understanding the molecular mechanisms by which impairments in accurate control of mRNA translation, cell growth, and overall cellular protein synthesis rates lead to cancer. The candidate will have the opportunity to publish their research in preeminent scientific journals such as Cell, Nature, Cancer Cell, and Molecular Cell. Previous researchers in this position have successfully obtained admission to some of the most prestigious MD, PhD, and MD-PhD programs in the country. This position will also include work in the Nguyen lab (https://nguyenlab.ucsf.edu), adjacent to the Ruggero lab, with an appointment effort of 100% split equally between the two labs.

Job Responsibilities:

Perform experiments and data analysis under direct supervision, with training provided. Primary tasks will include performing experiments utilizing western blot analysis, RNA isolation, PCR, tissue culture, mouse genotyping, immunohistochemistry, and mouse dissection. Additional duties will include participation in basic lab support activities, organization, as well as actively participating in group meetings.

Required Qualifications:

• Specialists appointed at the Junior rank must possess a bachelor's degree (or equivalent degree) in a relevant area of study, such as biochemistry, molecular biology, genetics, biology, or a related field, from an accredited college or university, or at least four years of research experience.
• Previous independent laboratory experience outside of required courses is mandatory.
• Must be highly motivated, clearly demonstrate a passion for scientific research, exhibit a strong commitment to perform scientific research, and have the willingness and ability to learn new methods and skills for changing research priorities.
• Must be an effective communicator, detail-oriented and organized, able to take the initiative to address research issues, and work independently, and collaborate well with other members of the lab.
• Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.
• Must be able to keep a complete and detailed laboratory notebook of experimental procedures and data and to archive, label, and document graphic and tabular data for publication, proposals, and/or presentations.
• Proficiency in MS Office and Adobe software, including Word, Excel, PowerPoint, Illustrator, and Photoshop.

Preferred Qualifications:

• Expertise working with RNA and basic molecular biology techniques, tissue culture, electrophoresis, DNA manipulation techniques, western blotting, immunoprecipitation, transfection, and flow cytometry.
• Experience with handling mice is highly preferred.
• Preference will be given to applicants with a minimum overall undergraduate GPA of 3.4.
• At least a 2-year commitment.
• Candidates interested in applying to graduate or medical school are encouraged to apply.

See Table 24B for the salary range for this position. A reasonable estimate for this position is $55,000-$58,600.

Applicants will be considered until the position is filled. Please apply online at https://aprecruit.ucsf.edu/JPF05904 with a cover letter, curriculum vitae, and provide a minimum of three names and email addresses of references from academic professionals supporting your research capability. Applicant materials must list current and/or pending qualifications upon submission. The selected candidate must meet all the qualifications at the time of appointment.

Document requirements

• Cover Letter
• Curriculum Vitae - CV must clearly list current and/or pending qualifications (e.g. board eligibility/certification, medical licensure, etc.).
• Statement of Research (Optional)

Reference requirements

• 3 required (contact information only)