Postdoctoral Fellowship in Mitochondrial Peroxiredoxins

Is the Job related to staff position within a Research Infrastructure?: No

Offer Description

Activities and context

A post-doctoral position is available to investigate mitochondrial peroxiredoxins (Prxs) in the response to oxidative stress and redox signaling. The project aims to understand: (i) the mechanisms that target Prxs to the mitochondrial matrix and intermembrane space (IMS); (ii) how Prxs in these compartments regulate peroxide homeostasis, including H2O2; and (iii) the functions of these proteins in the mitochondrial matrix and IMS. Yeast and human cell models will be employed, with a particular focus on the connections between mitochondrial Prxs, cancer, and ferroptosis.

Mandatory requirements

• Experience with redox proteins, peroxiredoxins, H2O2 metabolism, and/or mitochondrial biology;
• Experience with yeast and/or mammalian cell models;
• Experience with subcellular fractionation and protein localization studies;
• Knowledge of or experience with genetically encoded redox sensors and/or fluorescence microscopy;
• Ability to work independently and collaboratively in an interdisciplinary research team;
• Interest in contributing to the training and supervision of undergraduate and graduate students.

Desirable requirements

• Experience with redox proteins, peroxiredoxins, H2O2 metabolism, and/or mitochondrial biology;
• Experience with yeast and/or mammalian cell models;
• Experience with subcellular fractionation and protein localization studies;
• Knowledge of or experience with genetically encoded redox sensors and/or fluorescence microscopy;
• Ability to work independently and collaboratively in an interdisciplinary research team;
• Interest in contributing to the training and supervision of undergraduate and graduate students.

How to apply

Applicants should submit:

• Curriculum Vitae (FAPESP Summary Curriculum Vitae format), including a complete list of scientific publications;
• Motivation letter describing previous experience relevant to the project and interest in the position;
• A copy of the Ph.D. thesis;
• Names and two letters of recommendation.

Applications should be submitted by email with the subject line: “Application – FAPESP – funded Postdoctoral Fellowship in Mitochondrial Peroxiredoxins”.

For further information and to submit your application, please contact: Luis Netto; Email: nettoles@ib.usp.br.

This opportunity is open to candidates of any nationality. The selected candidate will receive a FAPESP Post-Doctoral fellowship in the amount of R$ 12,570.00 monthly and a research contingency fund, equivalent to 10% of the annual value of the fellowship which should be spent on items directly related to the research activity.

Where to apply

Website: http://www.fapesp.br/oportunidades/9881

Requirements

Additional Information

Eligibility criteria

Eligible destination country/ies for fellows:

• Brazil

Eligibility of fellows: country/ies of residence:

• All

Eligibility of fellows: nationality/ies:

• All

Work Location(s)

• Number of offers available: 1
• Company/Institute: Instituto de Biociências, Universidade de São Paulo (IB-USP)
• Country: Brazil
• State/Province: São Paulo
• City: São Paulo

Contact

• State/Province: São Paulo
• City: São Paulo
• Website: http://www.fapesp.br/oportunidades/
• Street: R. Pio XI, 1500 - Alto da Lapa
• Postal Code: 05468-901