Senior Cryo-electron Microscopy Scientist in Single Particle Analysis, Faculty of Biological Sciences

University of Leeds - School of Molecular & Cellular Biology

Location: Leeds

Salary: £51,753 to £59,966 per annum

Hours: Full Time

Contract Type: Permanent

Placed On: 7th October 2025

Closes: 5th November 2025

Job Ref: FBSMB1303

This role will be based on the university campus. We are open to discussing flexible working arrangements.

Would you like to play a leading role within the Astbury Biostructure Laboratory in Leeds? Do you have broad experience in biochemistry, structural biology and cryo-electron microscopy for single particle analysis? Do you have a passion for cutting edge biological and biomedical discovery, and delivering cutting edge outputs where the generation and analysis of data play a key role?

Working in the Astbury Biostructure laboratory with state-of-the-art experimental equipment and expertise in the field of cryo-electron microscopy, you will lead on the provision and development of single particle analysis services and workflows. You will play a key role in growing our userbase internally and externally, taking a proactive stance to bring attention to the excellence in single particle analysis services that can be found at the Astbury Biostructure Laboratory.

As an expert in the field, you will assist users by using experience-led and innovative methods in sample preparation, data collection and data processing for tackling a wide range of challenging samples. You will support research leaders at Leeds by assisting with the acquisition of research funding, contributing to high-quality publications, and by introducing the use of single particle analysis to new research areas.

For industrial clients, you will ensure the provision of industry standard services, maintaining clear communication and punctuality throughout the completion of work orders. You will act as an external facing representative of the facility to promote industrial user growth, creating opportunities to communicate and demonstrate the capabilities of the facility in providing tailored and expert-led services.

You should have a Ph.D. in Structural Molecular Biology and a passion for studying biological and biomedical processes, with extensive experience in preparing, imaging and analysing challenging specimens for cryo-electron microscopy for single particle analysis. As you will work closely and collaboratively with a wide range of researchers and lead new research projects, you will also have excellent communication skills.

To explore the post further or for any queries you may have, please contact:

Dr Louie Aspinall – Cryo-Electron Microscopy Facility Manager
Email: L.P.Aspinall@leeds.ac.uk