"PhD candidate multi-scale (MRI-microscopy) research in neurodegeneration"

Job Summary

Dementia is a global healthcare crisis affecting an estimated 55 million people worldwide. This project aims to develop pathology-sensitive MRI markers by combining post-mortem MRI and microscopy to monitor disease progression and treatment strategies in neurodegenerative diseases. It involves a unique collection of post-mortem neuroimaging data and collaborations with researchers at Leiden University Medical Center and the University of Pennsylvania (USA) to integrate clinical, radiological, and histopathological data for improved interpretation of imaging datasets.

Responsibilities

• Setting up and conducting the research;
• Collecting postmortem MRI scans;
• Performing immunohistochemical stainings at the lab;
• Performing MRI data analysis;
• Statistically analyzing MRI and neuropathology data;
• Writing scientific articles based on the results of your research;
• Making scripts publicly available through our GitHub site;
• Supervising students and some teaching duties.

Qualifications and Requirements

• A recent Master's degree in Neuroscience, Biomedical Science, or a related field with a proven interest in neurodegenerative diseases;
• Lab experience with immunohistochemistry on human brain tissue;
• Some programming skills is an advantage;
• Affinity with neuroimaging or eagerness to learn more;
• Highly motivated, creative, and willing to work with human postmortem MRI scans and brain tissue;
• Communicative, well-organized, independent, and enthusiastic.

What the Employer Offers

• A flying start to your career in scientific research;
• Plenty of room for your drive to shape tomorrow's healthcare;
• Working on large-scale and in-house research with motivated colleagues from all over the world;
• Employment by Amsterdam UMC Research BV;
• A contract for 12 months, with the intention to extend for a total of 4 years;
• Salary scale OIO: €3,108 to €3,939 gross based on full-time employment (depending on experience) and a year-end bonus of 8.3%;
• 190.4 holiday hours per year for full-time and a possibility to save additional hours;
• Pension accrual with BeFrank;
• 100% reimbursement for public transport travel costs over 7 km each way, or €0.18 per km for private transport up to 40 km each way;
• Bike scheme with reimbursement of €0.18 per km.