Postdoctoral Fellow

Company: Harvard University

Job Location: Cambridge, Massachusetts 02138

Category: Biochemistry and Molecular Biology

Type: Full-Time

School: Faculty of Arts and Sciences

Department/Area: Molecular and Cellular Biology/Applied Physics/SEAS

Position Description: Our lab is developing a series of cutting-edge methods to visualize cellular organization. As one example, we are using time-resolved cryo-vitrification (both cryo-plunging and high-pressure freezing) to visualize the nanoscale dynamics of cellular response to stimuli. In another direction, we are developing multicolor electron microscopy using the principle of "cathodoluminescence" - emission of light triggered by excitation with an electron beam. The advertised position involves further development of these and related methods as well as applications of these new technologies to address questions in the fundamental cell biology of transmembrane signaling through G-protein-coupled receptors and the formation of biomolecular condensates.

Basic Qualifications: Competitive applicants would typically have expertise in one or more of the following areas:

• Biophysical instrumentation development: optical and mechanical design, simulation, development and control
• Optical imaging; Single-molecule fluorescence and FRET; Lasers; Pump-probe experiments
• Biophysics of cell signaling and stress response; Biomolecular condensates; G-protein-coupled receptors (GPCRs); Cell and molecular biology
• Cryo-vitrification via cryo-plunging and high-pressure freezing; Time-resolved freezing
• Microfluidics; design, simulation, prototyping, fabrication and testing of fluidic devices
• Electron microscopy (cryo and regular) for structural and cell biology; Cathodoluminescence

Special Instructions: Letters of recommendation are not required at the time of application; however letters will be collected for finalists. Candidates should submit with their application contact information for three references from experts at the ladder faculty ranks or highly accomplished senior researchers from corporations or research institutes. Please include the following items as part of your application:

• Cover Letter
• Curriculum Vitae
• Summary of research experience and interests.
• Name and contact information for 3 references.

Contact Information: Professor Maxim Prigozhin Northwest Lab Building 52 Oxford Street Cambridge, MA 02138 Debra Maddalena (Administrator) maddalen@mcb.harvard.edu

Contact Email: maxim_prigozhin@harvard.edu

Equal Opportunity Employer: We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions or any other characteristic protected by law.

Minimum Number of References Required: 3

Maximum Number of References Allowed: 3