Research Technician

University of Oxford - Nuffield Department of Clinical Neurosciences (NDCN)

Location: Oxford

Salary: £34,982 to £40,855 per annum. RESEARCH GRADE 6

Hours: Part Time

Contract Type: Fixed-Term/Contract

Placed On: 5th September 2025

Closes: 3rd October 2025

Job Ref: 181892

Nuffield Department of Clinical Neurosciences (NDCN), West Wing, John Radcliffe Hospital, Headington, Oxford, OX3 9DU

This is an exciting opportunity to join a vibrant network of researchers within the NDCN to investigate the mechanisms underlying the development of neuropathic pain, a highly debilitating condition affecting approximately 9% of the population. The successful applicant will join the research team led by Associate Professor John Dawes, which focuses on the role of the immune system in pathological pain. Recent findings from the Dawes Lab have demonstrated that LGI1, a target of autoantibodies from neuropathic pain patients, plays a key role in regulating the severity of neuropathic pain. Building on these discoveries, this project will explore novel mechanisms linking LGI1 to pain regulation using transgenic mouse models, behavioural assays, cell culture, and electrophysiology. Key responsibilities will include lab management, technical support and assistance with experiments (e.g. immunohistochemistry, molecular biology, confocal imaging), maintenance of transgenic mouse colonies, curating clinical bio-samples and managing sample archives. Comprehensive training and support will be provided across all aspects of the project.

The appointed applicant would have a degree in a relevant scientific discipline, experience of working in a laboratory environment, as well as having the desire to learn new techniques and participant in collaborative projects.

For further information please email john.dawes@ndcn.ox.ac.uk

Please the 'Job Description' (via the 'Apply' button above) for further details on the responsibilities and selection criteria, as well as further information about the university and how to apply.

The post is part time at 0.8FTE for a fixed term of 2.5 years in the first instance, with possibility for extension.

Only applications received before 12.00 midday on Friday 3rd October will be considered.

Interviews will be held as soon as possible thereafter.