"Postdoctoral Fellow - Pulikkan Lab - Cancer Biology"

Job Details

A postdoctoral position is available at the Versiti Blood Research Institute (VBRI) and the Medical College of Wisconsin in Milwaukee, in the laboratory of Dr. John A. Pulikkan. The lab focuses on uncovering the mechanisms of leukemogenesis and identifying novel therapeutic targets in CEBPA mutant and inv(16) acute myeloid leukemia (AML). Recently, the lab developed the first conditional knock-in mouse model for CEBPA mutations in AML. Successful candidates will work on projects related to the therapeutic targeting of chromatin deregulation in CEBPA-mutant AML. These projects include in vivo leukemic studies (using genetic and patient-derived xenograft mouse models), CRISPR genome editing, in vitro differentiation, flow cytometry, and multi-omics approaches (ATAC-seq, CUT&Tag, RNA-seq, Hi-C). The position offers impactful publication opportunities, participation at international conferences, a competitive salary, and excellent career development prospects. It is supported by an NIH National Cancer Institute (NCI) R01 grant recently awarded to the Pulikkan lab. The role seeks a highly motivated, energetic, research-focused individual with a Ph.D. in Cancer Biology, Genetics, Biochemistry, or a related field. Successful candidates must have a proven track record of productivity and research experience and should be willing to work with mouse models.

About the Employer

Located in Milwaukee, Wisconsin, the Versiti Blood Research Institute (VBRI) is the largest blood-focused research institute in the United States. With over 40 basic, translational, and clinical researchers, the institute is dedicated to advancing scientific knowledge and developing innovative therapies related to blood and blood disorders. The institute's research interests cover a wide range of topics, including transfusion medicine, cellular therapy, thrombosis/hemostasis, immunology, and hematologic malignancies. As a vital part of Versiti, a non-profit organization with a blood bank at its core, the VBRI aims to improve lives through innovative research and the development of new diagnostics and treatments. VBRI is part of the Milwaukee Regional Medical Campus, a rapidly expanding clinical-translational research hub. Its proximity to the Medical College of Wisconsin (MCW), Children’s Hospital of Wisconsin, and Froedtert Hospital enables seamless interdisciplinary collaboration. As part of the MCW Cancer Center’s vibrant and collaborative campus, which is currently pursuing NCI Cancer Center designation, postdoctoral researchers will benefit from unique opportunities for interdisciplinary cancer research and professional development. Multiple top-tier core facilities at VBRI and MCW support highly competitive research. In summer 2024, construction began on a new research building, doubling the current VBRI research space to accommodate the recruitment of 10-15 new faculty members. With its renowned researchers, strategic growth plans, and location within a highly collaborative environment, VBRI is well-positioned to maintain and strengthen its status as one of the world’s leading hematology institutes.

How to Apply

The application should include a brief CV (no more than 3 pages), a research statement outlining past accomplishments, research interests, and career goals (one page), and contact information for three referees, all compiled into a single PDF sent to Dr. John A. Pulikkan, PhD at jpulikkan@versiti.org. For more information about the Pulikkan Lab, please visit: www.pulikkanlab.com.