University of Oxford  Jobs

Research Assistant in Motor Neuron Disease

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University of Oxford

Nuffield Department of Clinical Neurosciences (NDCN), John Radcliffe Hospital, Headington, Oxford, OX3 9DU

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Research Assistant in Motor Neuron Disease

Research Grade 6

2026-04-21 12:00 UK time

Location

John Radcliffe Hospital, Headington, Oxford, OX3 9DU

University of Oxford

Type

Full-time, Fixed-term (30 months)

Salary

£35,681 – £41,636 per annum

Required Qualifications

Bioscience graduate
iPSC neuronal/glial cultures
Motor/cortical neurons
Molecular & cellular biology
Neuroscience doctorate interest

Research Areas

Motor Neuron Disease (MND)
Amyotrophic Lateral Sclerosis (ALS)
Frontotemporal Dementia (FTD)
iPSCs
Neuroscience
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Research Assistant in Motor Neuron Disease

The Nuffield Department of Clinical Neurosciences (NDCN), John Radcliffe Hospital, Headington, Oxford, OX3 9DU seeks an enthusiastic Research Assistant for the opportunity to develop their expertise in Motor Neurone Disease (MND, also known as Amyotrophic Lateral Sclerosis, ALS, and the related disorder frontotemporal dementia, FTD) through their engagement with an established internationally-leading programme of neuroscience research led by Professor Kevin Talbot, Professor Martin Turner and Dr Alexander Thompson. You will be responsible for the provision of research support for the Motor Neuron Disease research group, contributing to the maintenance and analysis of neuronal and glial cultures derived from induced pluripotent stem cells (iPSCs) with ALS determining genetic variants. The post offers the opportunity to become proficient in the culture of motor and cortical neurons, microglia and astrocytes from iPSCs and to gain experience in the molecular and cellular biology of amyotrophic lateral sclerosis. As such the post would be very suitable for a bioscience graduate who is considering going on to study for a doctorate in neuroscience.

Please see the below 'Job Description' for further details on the role, responsibilities, and selection criteria, as well as further information about the university and how to apply.

This post is full time and fixed term for 30 months.

Only applications received before midday 12:00 on Tuesday 21st April 2026 will be considered.

Interviews will be held as soon as possible thereafter.

Contact Person: NDCN HR Recruitment | Vacancy ID: 185695 | Pay Scale: RESEARCH GRADE 6 | Salary: £35,681 – £41,636 per annum

recruitment@ndcn.ox.ac.uk

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Frequently Asked Questions

🔬What are the key responsibilities of the Research Assistant in Motor Neuron Disease?

You will provide research support to the Motor Neuron Disease group, maintaining and analyzing neuronal and glial cultures from iPSCs with ALS genetic variants. Gain proficiency in culturing motor/cortical neurons, microglia, and astrocytes, plus experience in molecular and cellular biology of amyotrophic lateral sclerosis. Ideal for advancing to a neuroscience doctorate. Explore similar roles in research assistant jobs or clinical research jobs.

🎓What qualifications are required for this Motor Neuron Disease Research Assistant position?

Suitable for a bioscience graduate interested in neuroscience. No specific prior experience listed, but enthusiasm for MND/ALS/FTD research and willingness to learn iPSC cultures and cellular biology is essential. Perfect stepping stone to a PhD in neuroscience. Check postdoctoral success tips and research jobs for preparation.

📅What is the application deadline and process for the Oxford MND Research Assistant role?

Applications must be received before midday 12:00 on Tuesday 21st April 2026. Interviews soon after. Contact NDCN HR Recruitment at recruitment@ndcn.ox.ac.uk (Vacancy ID: 185695). See full job description for details on responsibilities and selection criteria. Visit research assistant jobs for more opportunities.

💰What is the salary, contract duration, and employment type?

Salary: £35,681 – £41,636 per annum (Research Grade 6). Full-time, fixed-term for 30 months. Located at John Radcliffe Hospital, Oxford. Compare with professor salaries or university salaries for context in higher ed roles.

🎯Is this Research Assistant role suitable for aspiring PhD students in neuroscience?

Yes, explicitly "very suitable for a bioscience graduate who is considering going on to study for a doctorate in neuroscience." Develop expertise in MND (ALS/FTD), iPSC-derived cultures, and neuroscience research under leaders like Professors Talbot, Turner, and Dr. Thompson. Read how to excel as a research assistant for tips.

👥What research group and leaders will I work with?

Join the internationally-leading Motor Neuron Disease research group at Nuffield Department of Clinical Neurosciences, led by Professor Kevin Talbot, Professor Martin Turner, and Dr Alexander Thompson. Focus on ALS genetics and iPSC models. See related clinical research jobs.
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