"Research Investigator/Assistant Research Scientist/Associate Research Scientist/Research Scientist"

Job Overview

The Newman Lab, led by Dr. Erika A. Newman, MD, MBA and housed under the Section of Pediatric Surgery, is shifting the paradigm of pediatric neuroblastoma treatment. The Newman Lab is seeking a highly motivated and skilled Research Scientist to join a dynamic team focused on cutting-edge research in neuroblastoma, a pediatric cancer of the sympathetic nervous system. The successful candidate will contribute to ongoing projects investigating the molecular and cellular mechanisms driving neuroblastoma initiation, progression, and treatment resistance, and will play a key role in translational research efforts aimed at identifying novel therapeutic targets.

The academic rank for this position will be commensurate with the applicant's credentials.

Responsibilities

• Develop, design, and conduct more complex experiments in line with a research plan and review results periodically with faculty member or senior research staff member
• Perform molecular biology techniques (e.g., PCR, Western blotting, RNA-seq analysis, CRISPR/Cas9 editing)
• Write and collaborate with other researchers on manuscripts, abstracts, technical reports and other publications of research findings
• Contribute to grant writing and progress reports
• Provide instruction and technical support to academic trainees in the lab
• Direct day-to-day lab operations such as equipment maintenance and lab supply ordering
• Coordinate the collection and analysis of data and the conduct of experimental procedures

Required Qualifications

• PhD
• Exceptional written and verbal communication skills and ability to interact with and build professional relationships with all individuals at all levels
• Exceptional interpersonal skills and the ability to work independently and take initiative and within a team with minimal supervision
• Strong organizational skills and ability to effectively manage numerous projects, simultaneously and in various stages of development, with a high attention to detail
• Must have strong integrity, be highly proactive, have a high degree of problem-solving skills, be highly reliable, retain a sense of ownership and accountability for workload, be flexible and resilient, and possess expert follow-up skills
• Proven ability to prioritize and manage multiple tasks with competing deadlines
• Proven ability to write intramural and extramural grant proposals
• Proven ability to teach and/or train students, junior laboratory personnel in laboratory techniques and/or protocols

Preferred Qualifications

• PhD in Cancer Biology or related field
• More than 5 years of postdoctoral experience
• Strong background in cancer research, preferably in pediatric oncology or neuroblastoma
• Proficiency with mammalian cell culture, standard molecular/cellular biology techniques preferred
• Ability to work with CRISPR and Cre-Lox models
• Experience with identification and validation of drug targets, drug screening, target engagements and other standard cell biology techniques
• Familiarity in DNA damage studies and has previous experience in DNA damage biomarkers
• Familiarity with omics data (RNA-seq, ChIP-seq, proteomics) and analysis pipelines
• Knowledge of immunotherapy, epigenetics, or tumor microenvironment research
• Prior involvement in translational or drug discovery projects
• Familiarity with University research administration, policies and procedures

This position is posted as RESEARCH INVESTIGATOR/ASSISTANT RESEARCH SCIENTIST/ASSOCIATE RESEARCH SCIENTIST/RESEARCH SCIENTIST. The rank of the selected candidate will depend upon the candidate's qualifications. Applicants who do not meet criteria for the Research Scientist rank can be brought in at the Research Investigator, Assistant Research Scientist or Associate Research Scientist rank.

The University of Michigan is an equal employment opportunity employer.